Indications - Ropinirole is indicated for the treatment of the signs and symptoms of idiopathic Parkinson's disease. It is also indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).
Dosage & Administration - Dosing for Parkinson's disease: The recommended starting dose for Parkinson's disease is 0.25 mg three times daily. Based on individual patient therapeutic response and tolerability, if necessary, the dose should then be titrated with weekly increments as described below. Maximum recommended total daily dose of 24 mg (8 mg three times daily). Week 1: 0.25 mg 3 times daily. Total Daily Dose 0.75 mg Week 2: 0.5 mg 3 times daily. Total Daily Dose 1.50 mg Week 3: 0.75 mg 3 times daily. Total Daily Dose 2.25 mg Week 4: 1 mg 3 times daily. Total Daily Dose 3 mg Dosing for Restless Legs Syndrome: The recommended adult starting dose for RLS is 0.25 mg once daily 1 to 3 hours before bedtime. After 2 days, if necessary, the dose can be increased to 0.5 mg once daily, and to 1 mg once daily at the end of the first week of dosing, then as shown below as needed to achieve efficacy. Titration should be based on individual patient therapeutic response and tolerability, up to a maximum recommended dose of 4 mg daily. Days 1 and 2: 0.25 mg, 1 to 3 hours before bedtime, to be taken once daily Days 3-7: 0.5 mg, 1 to 3 hours before bedtime, to be taken once daily Days 2: 1 mg, 1 to 3 hours before bedtime, to be taken once daily Days 3: 1.5 mg, 1 to 3 hours before bedtime, to be taken once daily Days 4: 2 mg, 1 to 3 hours before bedtime, to be taken once daily Days 5: 2.5 mg, 1 to 3 hours before bedtime, to be taken once daily Days 6: 3 mg, 1 to 3 hours before bedtime, to be taken once daily Days 7: 4 mg, 1 to 3 hours before bedtime, to be taken once daily
Side Effects - The most common side effects of Ropinirole include fainting, drowsiness, hallucinations, dizziness, nausea or vomiting, uncontrolled sudden movements, leg swelling, fatigue, confusion, headache, upset stomach, abdominal pain or discomfort, increased sweating etc.
Contraindications - It is contraindicated in patients known to have a hypersensitivity to Ropinirole.
Others - Pregnancy & Lactation Pregnancy category C. There is no adequate and well-controlled studies in pregnant women. It should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Ropinirole inhibits prolactin secretion in human and could potentially inhibit lactation.
Tablet Perkirol 0.25 mg
- Brand Name - Perkirol 0.25 Tablet
- Generic Name - Ropinirole
- Doges From - Tablet
- Strength - 0.25 mg
- Pack Size - 50s
- Manufacture - Square Pharmaceutical Ltd.
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