Indications - Clobetasol Propionate is indicated for adults, elderly and children over 1 year in following dermatoses. Psoriasis (excluding widespread plaque psoriasis) Recalcitrant dermatoses Lichen planus Discoid lupus erythematosus Other skin conditions which do not respond satisfactorily to less potent steroids
Dosage & Administration - Once or twice daily until improvement occurs, should not be continued for more than four weeks
Side Effects - The most reported side effects are burning and stinging sensation. Less frequent adverse reactions are itching, skin atrophy, cracking and fissuring of the skin. Cushing syndrome has been reported in infants and adults as a result of prolonged use of topical Clobetasol Propionate formulations.
Contraindications - It is contraindicated in patient with hypersensitivity to any component of the preparation. It should not be used in rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, pruritus without inflammation, untreated cutaneous infections.
Others - Pregnancy & Lactation There are limited data from the use of Clobetasol Propionate cream in pregnant women. Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development. The relevance of this finding to humans has not been established. However, the administration of Clobetasol Propionate Cream during pregnancy and lactation should only be considered if the expected benefit to the mother outweighs the possible risks of treatment. It is unknown whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Clobetasol Propionate Cream is administered to a nursing woman.