Indications - Hyperammonemia • Acute and Chronic liver diseases such as - Liver cirrhosis - Fatty liver - Hepatitis • Hepatic encephalopathy
Dosage & Administration - Dosage Sachet: 1-2 sachets granules is dissolved in a large amount of fluid (e.g. in a glass of water or juice) and is taken orally 3 times a day during or after meals. Injection (Infusion Concentrate): The recommended dose is up to 20 gm (4 ampoules daily). In case of loss of consciousness (pre-coma) and clouding of consciousness (coma) up to 8 ampoules within 24 hours, depending on the severity of the condition. Administration L-Ornithine L-Aspartate infusion concentrate can be added to any of the conventional intravenous fluids (0.9% Sodium Chloride, 5% Dextrose and Ringer's lactate etc.) The normal dilution rate is 1 ampoule per 100 ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml infusion. The solution mixtures were stable up to 24 hours. Infusion Rate: 5 gm/h at maximum.
Side Effects - Very rarely side effects like nausea and vomiting occur. These side effects are usually transient and do not necessitate the withdrawal of the drug.
Contraindications - Data not found
Others - Pregnancy & Lactation The administration in pregnancy and lactation should be avoided. Precautions & Warnings Monitoring of serum and urinary urea levels at regular intervals should be done.
Hepagurd Oral Powder
- Brand Name - Hepagurd Powder 3 gm/sachet
- Generic Name - L-Ornithine L-Aspartate
- Doges From - sachet
- Strength - 3 gm
- Pack Size - 1s
- Manufacture - Beximco Pharmaceuticals Ltd
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