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Indications - Vitamin B1, B6 & B12 is indicated for the treatment of vitamin B1, B6 & B12 deficiency syndrome. It is also indicated for the supportive treatment of neuritis & non-inflammatory diseases of the nerves, e.g.- Diabetic neuropathy Peripheral neuralgin Lumbago Myalgia Optic neuritis Sciatica Facial neuralgia Intercostal neuralgia Spinal pain.

Dosage & Administration - Tablet: 1-3 Tablets per day or as advised by the physician. Injection: In severe (acute) cases: 1 injection daily until the acute symptoms subside or taken as advised by the physician. In mild cases: 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly. Use in children: There is no information on the use of this drug in children.

Side Effects - Generally well tolerated but allergic reactions may be observed in few cases.

Contraindications - Vitamin B1, Vitamin B6 and Vitamin B12 is contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation.

Others - Pregnancy & Lactation Oral tablet form is recommended but due to the presence of benzyl alcohol, injection is not recommended during pregnancy & lactation. Precautions & Warnings Cyanocobalamin should not be given in patients with subacute degeneration of the spinal cord. Cyanocobalamin is not suitable form of vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin. Overdose Effects No overdosage symptoms are to be expected in the recommended dosage. If there is known overdose then treatment is symptomatic & supportive.