Indications - Prevention of skeletal related events (pathological fracture, radiation to bone, spinal cord compression or bone surgery) in patients with bone metastases from solid tumours.
Dosage & Administration - Subcutaneous Injection: 120 mg once every 4 wk into thigh, abdomen or upper arm. Ca & vitamin D supplements should be given whilst undergoing treatment.
Side Effects - Dyspnoea, Hypocalcaemia, hypophosphataemia, Osteonecrosis of the Jaw (ONJ).
Contraindications - Hypersensitivity to denosumab or to any of the excipients.
Others - Pregnancy & Lactation Pregnancy Category D. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Denosis 120 Injection
- Brand Name - Denosis 120 Injection
- Generic Name - Denosumab
- Doges From - Injection
- Strength - 120 mg/1.7 ml
- Pack Size - 1s
- Manufacture - Incepta Pharmaceuticals Ltd.
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