Logo

Indications - Dopamine is recommended for the correction of haemodynamic imbalance present in- Acute hypotension or shock associated with myocardial infarction, endotoxic septicaemia, trauma and renal failure. As an adjunct after open heart surgery, where there is persistent hypotension after correction of hypovolaemia. In chronic cardiac decompensation as in congestive failure.

Dosage & Administration - Intravenous- Acute heart failure: Adult: Initially, 2-5 mcg/kg/min, increased gradually by up to 5-10 mcg/kg/min according to patient’s cardiac and urine output. Seriously ill patient: Up to 20-50 mcg/kg/min may be required.

Side Effects - Ectopic heartbeats, angina, tachycardia, palpitation, hypotension, vasoconstriction, dyspnoea, nausea, vomiting, headache, cardiac conduction abnormalities, HTN, azotemia, anxiety, widened QRS complex, bradycardia, piloerection, peripheral cyanosis.

Contraindications - Administration of dopamine is contraindicated in the following cases: Pheochromocytoma, atrial or ventricular tachyarrhythmias, ventricular fibrillation, hyperthyroidism, concurrent use with ergotamine.

Others - Pregnancy & Lactation Pregnancy: It is not known whether dopamine crosses the placental barrier. The benefits of using this product should be weighed against the possible risks to the fetus. Lactation: It is not recommended for breast-feeding mothers unless the expected benefits outweigh any potential risks.