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Indications - In low doses- nervousness, anxiety states and associated psychic disorders as irritability gressiveness, psychic lability and insomnia functional disorders caused by anxiety states such as trembling, thorax oppression, gastrointestinal hypermotility and digestive disorders tics and stuttering nausea and vomiting In higher doses- psychomotor agitation in mania, dementia, acute and chronic schizophrenia, alcoholism delusions and hallucinations in acute and chronic schizophrenia, acute confusion choreatic movements behavior and character disorders in children tics and stuttering vomiting

Dosage & Administration - Tablet- Initial dose for adults- Moderate symptomatology: 0.5 mg to 3.0 mg 2 to 3 times daily Severe symptomatology: 3.0 mg to 5.0 mg 2 to 3 times daily Elderly patients: 0.5 mg to 4.5 mg 2 to 3 times daily Chronic or Resistant patients: 3.0 mg to 6.0 mg 2 to 3 times daily Patients who remain severely disturbed or inadequately controlled may require dose adjustment. Daily dose upto 100 mg may be necessary in some cases to achieve optimal response. Children: A suggested dose for the management of behaviour disorders in disturbed and schizophrenic children is 50 microgram per kg body weight. Injection (intramuscular or intravenous)- Schizophrenia and other psychosis, mania: Initially 2-10 mg, then every 4-8 hours according to response to total maximum 18 mg daily Severely disturbed patients may require an initial dose of up to 18 mg Elderly (or debilitated) initially half adult dose For children not recommended.

Side Effects - Haloperidol is a safe neuroleptic. Headache, vertigo, insomnia are the more common side effects encountered. Drowsiness, lethargy, stupor, confusion, restlessness, agitation, anxiety, euphoria and exacerbation of psychotic symptoms including hallucinations also may occur. Dry mouth, blurred vision, urinary retention, heartburn, nausea, vomiting, anorexia, diarrhea and hypersalivation have also been reported.

Contraindications - Comatose states and CNS depression due to alcohol or other depressant drugs; severe depressive states; previous spastic diseases; lesions of the basal ganglia; Parkinson's syndrome, except in the case of dyskinesias due to levodopa treatment; sensitivity to haloperidol; senile patients with pre-existing Parkinson-like symptoms.

Others - Pregnancy & Lactation Safety for use in pregnancy and lactation has not been established; do not administer to women of childbearing potential or nursing mothers unless, in the opinion of the physician, the expected benefits of the drug outweigh the potential hazard to the fetus or child. Haloperidol is excreted in breast milk.