Indications - ketoconazole 2% shampoo is indicated for the treatment and prophylaxis of infections in which the yeast Malassezia (previously called Pityrosporum) is involved, such as pityriasis versicolor (localized), seborrhoeic dermatitis and pityriasis capitis (dandruff).
Dosage & Administration - The affected areas of the skin or the scalp should be washed with ketoconazole 2% shampoo, which should be left on the skin/scalp for 3 to 5 minutes before rinsing. Treatment: Pityriasis versicolor: Once daily for 5 days. Seborrhoeic dermatitis and pityriasis capitis: Twice weekly for 2 to 4 weeks. Prophylaxis: Pityriasis versicolor: Once daily for 3 days during a single treatment course before the summer. Seborrhoeic dermatitis and pityriasis capitis: Once every 1 or 2 weeks
Side Effects - Topical treatment with ketoconazole shampoo 2% is generally well tolerated. As with other shampoos, a local burning sensation, itching or contact dermatitis (due to irritation or allergy) may occur on exposed areas. Oily and dry hair have been reported rarely with the use of ketoconazole shampoo 2%.
Contraindications - Contraindicated in patients with known hypersensitivity to ketoconazole.
Others - Pregnancy & Lactation Since ketoconazole is not absorbed through the skin after topical application, pregnancy and lactation are not a contraindication for the use of ketoconazole shampoo 2%.