Indications - Ketorolac Tromethamine is indicated for the short-term management of moderate to severe acute post-operative pain.
Dosage & Administration - Tablets: 10 mg every 6 hours as required up to 7 days. Injection: For adults (65 years): Initial dose is 60 mg IM (Single). Maintenance dose is 30 mg IM/IV 6 hourly. Maximum dose is 120 mg/day. For adults (>65 years): Initial dose is 30 mg IM. Maintenance dose is 10-15 mg IM/IV 6 hourly. The maximum duration of treatment should not exceed two days
Side Effects - Commonly occurring side effects are nausea, vomiting, gastro-intestinal bleeding, melana, peptic ulcer, pancreatitis, anxiety, drowsiness, headache, excessive thirst, fatigue, bradycardia, hypertension, palpitation, chest pain, infertility in female and pulmonary edema.
Contraindications - Ketorolac is contraindicated in patients having hypersensitivity to this drug or other NSAIDs. It should not be used in children under 16 years of age. lt is also contraindicated as prophylactic analgesic before surgery.
Others - Pregnancy & Lactation US FDA Pregnancy category of Ketorolac Tromethamine is C. So, Ketorolac Tromethamine should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.