Indications - Valacyclovir is indicated for the treatment of Herpes zoster (shingles). It is indicated for the treatment or suppression of genital herpes in immuno-competent individuals and for the suppression of recurrent genital herpes in HIV infected individuals. It is also indicated for the treatment of cold sores (Herpes labialis).
Dosage & Administration - Adult Dosage: Cold Sores: 2 grams every 12 hours for 1 day Genital Herpes: Initial episode: 1 gram twice daily for 10 days Recurrent episodes: 500 mg twice daily for 3 days Suppressive therapy Immunocompetent patients: 1 gram once daily Alternate dose in patients with < 9 recurrences/year: 500 mg once daily HIV-infected patients: 500 mg twice daily Reduction of transmission: 500 mg once daily Herpes Zoster: 1 gram 3 times daily for 7 days Pediatric Dosage: Cold Sores (> 12 years of age): 2 grams every 12 hours for 1 day Chickenpox (2 to < 18 years of age): 20 mg/kg 3 times daily for 5 days; not to exceed 1 gram 3 times daily
Side Effects - The most frequently reported adverse reactions were nausea (15%), headache (14%), vomiting (6%), dizziness (3%) and abdominal pain (3%).
Contraindications - Valacyclovir is contraindicated in patients with a known hypersensitivity or intolerance to valacyclovir, acyclovir, or any component of the formulation.
Others - Pregnancy & Lactation Pregnancy category B. Valacyclovir was not teratogenic in rats or rabbits at 10 and 7 times human plasma levels, respectively, during the period of major organogenesis. There is no adequate and well-controlled studies of valacyclovir in pregnant women. Nursing Mothers: Unchanged valacyclovir was not detected in maternal serum, breast milk, or infant urine. Valacyclovir should be administered to a nursing mother with caution and only when indicated.
Valovir 1gm Tablet
- Brand Name - Valovir 1 gm Tablet
- Generic Name - Valacyclovir
- Doges From - Tablet
- Strength - 1 gm
- Pack Size - 8s
- Manufacture - Incepta Pharmaceuticals Ltd.
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