Indications - Allylestrenol is indicated in: Intra Uterine Growth Retardation (IUGR) Threatened abortion Habitual abortion Threatened premature delivery
Dosage & Administration - Intra Uterine Growth Retardation: 1 tablet three times a day at least two months. Dose to be reduced if symptoms improve. Threatened abortion: 1 tablet three times daily until symptoms disappear. Habitual abortion: 1-2 tablets daily as soon as pregnancy is diagnosed. The administration should be continued for at least one month after the end of the critical period. Threatened premature delivery: Dosage must be determined individually. High dosages (up to 40 mg daily) have been used. In case of a missed dose, it should be taken as soon as the patient remembers & she should continue the regular dosing schedule. A double dose is not recommended.
Side Effects - Treatment with Allylestrenol (especially a long term treatment) is known to cause some gastrointestinal complaints such as vomiting, nausea, and sometimes epigastric discomfort.
Contraindications - Hypersensitivity; thrombophlebitis; undiagnosed vaginal bleeding, incomplete abortion, hormone-dependent carcinoma, cerebral apoplexy, as a diagnostic test for pregnancy; severe hepatic impairment.
Others - Pregnancy & Lactation Allylestrenol is specifically designed to be taken during pregnancy. It should be discontinued after delivery as it may affect a nursing infant to a small but noticeable degree. Precautions & Warnings Patients with the following conditions should be cautious: Heart disease, congestive heart failure, sick sinus syndrome, coronary artery disease, seizures, epilepsy, renal dysfunction, migraine headaches, or breathing diseases including asthma, emphysema, chronic bronchitis, or COPD, breast-feeding. Use in Special Populations It should not be used for children younger than 16 years old. Overdose Effects Symptoms of overdose may include unusual drowsiness; rapid pulse; fainting; unusual muscle movement or rigidity of the face, neck, or limbs; seizures; and loss of consciousness. Storage Conditions Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children