Indications - Amoxicillin is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis) Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis) Skin and soft tissue infections (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess) Genito-urinary tract infections (i.e. pyelonephritis, cystitis and urethritis) Venereal disease (i.e. acute uncomplicated gonorrhoea) In dental abscess, it is used as short-term therapy. It is also indicated in combination with Clarithromycin and Lansoprazole (as triple therapy), for the treatment of patients with H. pylori infection and duodenal ulcer disease and to reduce the risk of duodenal ulcer recurrence.
Dosage & Administration - Dosage Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections. Children (up to 10 years of age) : 125 mg three times daily, increasing up to 250 mg three times daily for severe infections. Severe or recurrent purulent respiratory infection: 3 gm every 12 hours. Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily). Pneumonia: Recommended dose is 500-1000 mg three times daily. Dental abscess: Recommended dose is 3 gm, repeated after 10-12 hours. Urinary tract infections: Recommended dose is 3 gm, repeated after 10-12 hours. Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years). In renal impairment: it may be necessary to reduce the total daily dosage. Administration Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water. These preparations should then be taken immediately.
Side Effects - Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.
Contraindications - Amoxicillin is contraindicated in penicillin hypersensitive patients.
Others - Amoxicillin is contraindicated in penicillin hypersensitive patients.
Capsule Moxacil 500mg
- Brand Name - Moxacil 500 Capsule
- Generic Name - Amoxicillin Trihydrate
- Doges From - Capsule
- Strength - 500 mg
- Pack Size - 100s
- Manufacture - Square Pharmaceutical Ltd.
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