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Indications - Estriol cream is indicated for the defficiency of estrogen. During menopause, the amount of estrogens produced by a woman's body gradually drops. Shortage of estrogens causes the vaginal wall to become thin and dry which leads to painful sexual intercourse. Estriol cream is used to relieve painful sexual intercourse. This is used in postmenopausal women with at least 12 months since their last natural period. If the ovaries are removed surgically (ovariectomy) before menopause, the decrease in estrogen production occurs very abruptly.

Dosage & Administration - Vaginal Atrophy: 1 application per day for the first weeks, followed by a gradual reduction. (e.g. 1 application twice a week). • Pre- and post-operative therapy in postmenopausal women undergoing vaginal surgery: 1 application per day 2 weeks before surgery; 1 application twice a week up to 2 weeks after surgery. • Labial Adhesions: 1-2 times daily for 2 months

Side Effects - Local irritation or itching of vagina, Swelling and increased tenderness of the breasts, Increased vaginal discharge, Nausea, Fluid retention in the tissues, usually marked by swollen ankles or feet. In most patients these side effects will disappear after the first weeks of treatment. Tell your doctor if vaginal bleeding occurs or if any side effect becomes troublesome or persists. Other side effects which may occur with HRT are benign and malignant hormone-dependent tumors such as endometrial cancer, heart attack and stroke, gall bladder disease, skin problems such as rashes, discoloration or red patches on the skin, various skin diseases with blisters and nodules or bleeding into the skin, venous thromboembolism or deep leg or pelvic venous thrombosis and pulmonary embolism (see Before you use Estriol Cream). Using HRT for several years slightly increases the risk of breast cancer

Contraindications - Data not show

Others - Pregnancy & Lactation This medicine is contraindicated during pregnancy & lactation.