Indications - Lubiprostone is indicated in: Irritable Bowel Syndrome with Constipation (IBS-C). Chronic Idiopathic Constipation (CIC) in adults. Opioid-Induced Constipation (OIC) in adult patients with chronic, non-cancer pain.
Dosage & Administration - Irritable Bowel Syndrome with Constipation: The recommended dose is 8 mcg twice daily orally with food and water. Dosage in patients with hepatic impairment: Dosage adjustment is not required for patients with moderately impaired hepatic function. For patients with severely impaired hepatic function, the recommended starting dose is 8 mcg once daily. If tolerated then dose can be increased to 8 mcg twice Chronic Idiopathic Constipation and Opioid-induced Constipation: The recommended dose is 24 mcg twice daily orally with food and water. Dosage in patients with hepatic impairment: For patients with moderately impaired hepatic function, the recommended starting dose is 16 mcg twice daily. For patients with severely impaired hepatic function, the recommended starting dose is 8 mcg twice daily.
Side Effects - Diarrhea, full or bloated feeling or pressure in the stomach, nausea, stomach pain, swelling of abdominal or stomach area, Dyspnea
Contraindications - Lubiprostone is contraindicated in patients with known or suspected mechanical gastrointestinal obstruction.
Others - Pregnancy & Lactation Pregnancy category C. It is not known whether lubiprostone is excreted in human milk. Because lubiprostone increases fluid secretion in the intestine and intestinal motility, human milk-fed infants should be monitored for diarrhea. Caution should be exercised when Lubiprostone is administered to a nursing woman.
Capsule Gutfix 8 mcg
- Brand Name - Gutfix 8mcg Soft Gelatin Capsule
- Generic Name - Lubiprostone
- Doges From - Capsule
- Strength - 8 mcg
- Pack Size - 20s
- Manufacture - Square Pharmaceutical Ltd.
Customers who bought this item also bought
