Logo

Indications - Aspirin is indicated in the following indications- Prophylaxis against arterial occlusive events: Myocardial infarction, myocardial re-infarction, after bypass surgery, acute ischaemic stroke/TIA. Mild to moderate pain: Headache, muscle pain, dysmenorrhoea and toothache etc. Chronic disease accompanied by pain and inflammation: Osteoarthritis. Antipyretic: Cold fever and influenzae.

Dosage & Administration - Pain, inflammatory diseases and as antipyretic: Aspirin 300 mg 1-3 tablets 6 hourly with a maximum daily dose of 4 gm. Suspected acute coronary syndrome: 150 mg-300 mg immediately unless there are clear contraindications. After myocardial infarction: Aspirin 150 mg daily for 1 month. Long-term use of aspirin in a dose of 75 mg daily is recommended thereafter. Acute ischaemic stroke/Transient ischaemic stroke (TIA): The starting dose is 150 mg-300 mg daily and Aspirin 75 mg daily thereafter. Following bypass surgery: 75 mg-300 mg daily starting 6 hours post-procedure.

Side Effects - Side effects for the usual dosage of Aspirin are mild including nausea, dyspepsia, gastrointestinal ulceration and bronchospasm etc.

Contraindications - Aspirin is contraindicated to the children (Reye's syndrome) less than 12 years, in breast-feeding and active peptic ulcer. It is also contraindicated in bleeding due to haemophilia, intracranial haemorrhage and other ulceration.

Others - Pregnancy & Lactation It is especially important not to use aspirin during the last 3 months of pregnancy unless specifically directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Aspirin penetrates into breast milk. So, it should be administered with caution to lactating mothers.