Indications - Diazepam is indicated for the short-term treatment of mild to moderate anxiety, excitation, agitation, fear, aggressiveness, etc. Anxiety reactions caused by stressed conditions, anxiety states with somatic expression, acute alcohol withdrawal, status epilepticus, premedication for surgical procedures, febrile convulsions, insomnia of hospitalized patients.
Dosage & Administration - Oral: Anxiety: 2 mg thrice daily, increased if necessary to 15-30 mg daily in divided doses. Elderly (or debilitated), half of the adult dose. Insomnia associated with anxiety: 5-15 mg at bedtime. Night terrors and somnambulism in Child: 1-5 mg at bedtime. IM/slow IV injection (large vein, a rate below 5 mg/minute): For severe acute anxiety, control of acute panic attacks, and acute alcohol withdrawal: 10 mg repeated if necessary after not less than 4 hours. Febrile convulsion in children: Slow IV in a dose of 250 mcg/kg. Rectal: In case of children- A dose of 500 mcg/kg (maximum 10 mg), repeated if necessary.
Side Effects - Diazepam is generally well tolerated. Higher doses may cause somnolence, dizziness, light headedness, confusion and ataxia.
Contraindications - Diazepam is contraindicated in myasthenia gravis, pulmonary insufficiency, respiratory depression and hypersensitivity to bezodiazepine.
Others - Pregnancy & Lactation Diazepam and its active metabolites cross the placental barrier and also pass into breast milk. So, it should be avoided if possible during pregnancy and lactation. US FDA pregnancy category D.
Sedil Injection
- Brand Name - Sedil Injection
- Generic Name - Diazepam
- Doges From - Injection
- Strength - 10 mg
- Pack Size - 10s
- Manufacture - Square Pharmaceutical Ltd.
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